Susan Melinda Yeagley was born and raised in Nashville, Tennessee. The younger of two daughters, Susan left the South at 18 to attend the University of Southern California. She earned her B.A. degree from USC's famed film school, where she graduated Cum Laude and was a member of the National Honor Society and Dean's List. Upon graduation, Susan took a comedy class at the Groundlings and several classes later, ended up a member of the Groundlings Sunday Company, where she performed sketch comedy and improv. An agent saw her perform in the Sunday show and Susan was signed and began working.